The current implementation for wildcard blacklisting doesn’t really use wildcards. All it really is, is blocking of domains and all subdomains.
The announcement mentions youtube ad blocking, sadly the implementation doesn’t allow for youtube ad blocking without blocking non-ad subdomains as well.
My suggestion is simple: allow real wildcards. For example blocking youtube ads would require to block “r*—sn-*.googlevideo.com” where * could be anything.
It would be nice to have something more precise (maybe regex statements), but even the ability to add real wildcards would allow for proper blocking of only certain subdomains.